I encountered this error on my on-premise/Hybrid exchange server today after noticing that internal mail relay was not working. When attempting to send a test email via telnet, I got the error 451 4.7.0 Temporary server error. Please try again later. PRX5
After rebooting the server, the error still persisted - so a quick bit of searching quickly lead to me adjusting the Exchange servers DNS settings.
From within Exchange Control Panel (ECP) - go to Servers (left hand menu) and double click your Exchange server to open it's properties
Select DNS Lookups from the left menu.
By default, the option for External and Internal DNS lookups is usually All network adapters (All available IPv4). I changed this to Microsoft Hyper-V Network Adapter and the problem was immediately resolved.
For me, the problem ultimately was on the DNS server on the DomainController
ReplyDeleteThe A record for the Exchange server still referred to the old IP address after it was migrated, after i change it to the new Ip adres and reboted the exchange server it works